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Gregory House
Gregory House, M.D. is a misanthropic, cynical, narcissist, and curmudgeon who leads a team of diagnosticians and is the Head of Diagnostic Medicine at the fictional Princeton-Plainsboro Teaching Hospital in Princeton, New Jersey. House's unorthodox diagnostic approaches, radical therapeutic motives, and stalwart rationality have resulted in much conflict between him and his colleagues. He is also often portrayed as lacking sympathy for his patients, a practice that allows him time to solve pathological enigmas.